25 Deadliest Diseases in Human History

As violent as we can be towards one another, throughout history, the biggest executioner of the human race has been deadly disease. Whether it was the Black Death in 14th century Europe or Ebola in present day Africa, the loss of human life and cost to society has been astronomical. These are the 25 deadliest diseases in human history.

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Lung Cancer


On a worldwide scale, lung cancer is the most common cancer-related death in men and women, responsible for 1.38 million deaths annually.



stomach pain

A common cause of death in third world countries and the second most common cause of infant deaths worldwide, the loss of fluids through diarrhea can cause dehydration and electrolyte disturbances such as potassium deficiency or other salt imbalances.


Perinatal Complications


Each year, about 500,000 women die worldwide from complications related to pregnancy and childbirth, including severe bleeding/hemorrhaging, infections, unsafe abortions, obstructed labor and eclampsia. More than 90 percent of maternal deaths occur in Asia and sub-Saharan Africa.


Whooping Cough

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Technically known as Pertussis, this highly infectious disease is known in some countries as the “cough of 100 days.” It’s estimated that the disease affects 48.5 million people yearly, resulting in nearly 295,000 deaths.



ebola isolation

Deriving its name from the Ebola River in Republic of the Congo, where it was first found, its victims typically suffer fevers, muscle weakness, and other symptoms that progress to severe bleeding, both internal and external, that eventually causes them to bleed to death. Unfortunately, there is no treatment as of yet. Most of us remember a few years back when there was one of the worst outbreaks in history, with some cases popping up even in the US.

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